General Cell Lines and Cell Cultures
Biochain Institute Inc Paraffin Tissue Section - Human Adult Normal: Skeletal Muscle, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Biochain Institute Inc Frozen Tissue Section - Progressive Supranuclear Palsy: Brain: Occipital Lobe, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
ATCC Staphylococcus haemolyticus; Strain SM 131
Staphylococcus haemolyticus strain SM 131 [DSM 20263] is a whole-genome sequenced type strain that was isolated from human skin. This bacterial culture can be used as a quality control strain for API products.
Genscript Corporation CHO-K1/mouse PD-L1 Stable Cell
Recombinant CHO-K1 cells stably overexpress mouse programmed cell death 1 ligand 1 (PD-L1) on the surface The surface expression of PD-L1 is validated by FACS analysis
Eurofins Discoverx ChemiScreen CGRP1 Calcitonin Receptor-Like Receptor Stable Cell Line, 2 vials. (HTS172C)
The ChemiScreen CGRP1 Calcitonin Receptor-Like Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. calcitonin) based activation of CALCRL - RAMP1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses CALCRL alongside RAMP1 modifying protein and endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of CALCRL, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC BT54; Oligodendroglioma; Human (Homo sapiens)
BT54 is a cell line with bright smooth spheres morphology that was isolated in 2007 from the brain of a 49-year-old female with oligodendroglioma. It can be used for neuroscience and cancer research.
Eurofins Discoverx Ready-to-Assay GAL1 Galanin Receptor Frozen Cells, 2 Vials of Cells. (HTS094RTA)
The Ready-to-Assay GAL1 Galanin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. galanin) based activation of GALR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses GALR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of GALR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx PathHunter CHO-K1 AVPR1B β-Arrestin Cell Line, 2 vials. (93-0486C2)
The PathHunter AVPR1B cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. testosterone, norgestrel) based activation of AVPR1B GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged AVPR1B and EA-tagged β-Arrestin-2. Activation of AVPR1B stimulates the recruitment of β-Arrestin-2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, User Manual and datasheet, visit www.discoverx.com/gpcr.